INDUCED PLURIPOTENT STEM CELL-DERIVED MESENCHYMAL STEM CELLS DELIVER EXOGENOUS MIR-105-5P VIA SMALL EXTRACELLULAR VESICLES TO REJUVENATE SENESCENT NUCLEUS PULPOSUS CELLS AND ATTENUATE INTERVERTEBRAL DISC DEGENERATION

Abstract Background Mesenchymal stem cell-derived small extracellular vesicles (MSC-sEVs) have emerged as click here a promising new therapeutic strategy for intervertebral disc degeneration (IVDD).However, the drawbacks of MSCs, including their invasive access, the donor age, and their limited proliferative capacity, hinder the quantity and qualit

The outbreak of Coronavirus was first reported from Wuhan, Hubei, China on the end month of 2019.Due to its rapid outbreak and quick transmission, the World Health Organization (WHO) declared it as an ongoing pandemic.The available viral influenza medicines are found to be ineffective to treat COVID-19,so there is a need of strong technology click

Prior to the advent of chlorinated hydrocarbons, organophosphates, and carbamates the little fire ant, Wasmannia auropunctata (Roger), was a problem in Florida.The use of persistent pesticide chemicals reduced click here the populations of the ants until they were no longer a menace.With the reduction in the use of these persistent pesticide chemic

The background of this research is that it is not easy to create a Bintara Police student from civil society to become a member of the National Police.The backgrounds of students who come from a variety of characters and different educational backgrounds become obstacles in forming non-commissioned police officers, especially students who have just

Abstract Swimming in low-Reynolds-number fluids requires the breaking of time-reversal symmetry and centrosymmetry.Microswimmers, often with asymmetric shapes, exhibit nonreciprocal motions or exploit nonequilibrium processes to propel.The role of the surrounding fluid has also attracted attention because opi the color that keeps on giving viscoela